P107

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P107

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N6-(2-Phenylethyl)adenosine

CAS Number:20125-39-7
Linear Formula:C18H21N5O4
Molecular Weight:371.39
MDL number:MFCD00055128

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Description

Biochem/physiol ActionsSelective A1 adenosine receptor agonist.

Properties

solubility0.1 M NaOH: soluble
 H2O:  very slightly soluble
 ethanol:  moderately soluble
Gene Informationhuman ... ADORA1(134)

Safety

Personal Protective EquipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany3

References

referenceKusachi, Dog coronary artery adenosine receptor: Structure of the N6-alkyl subregion. J. Med. Chem. 38, 1636, (1985)
 Daly, Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow. Biochem. Pharmacol. 35, 2467, (1986)
 Dunwiddie, Adenosine analogs mediating depressant effects of synaptic transmission in rat hippocampus: Structure-activity relationships for the N6 subregion. Naunyn Schmiedebergs Arch. Pharmacol. 334, 77, (1986)